Atypical cell cycle regulation promotes mammary stem cell expansion during mammary development and tumourigenesis
Abstract Background The cell cycle of mammary stem cells must be tightly regulated to ensure normal homeostasis of the mammary gland to prevent abnormal proliferation and susceptibility to tumorigenesis. The atypical cell cycle regulator, Spy1 can override cell cycle checkpoints, including those act...
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| Principais autores: | , , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
BMC
2024-06-01
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| 丛编: | Breast Cancer Research |
| 主题: | |
| 在线阅读: | https://doi.org/10.1186/s13058-024-01862-1 |
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