Cancer cell intrinsic TIM-3 induces glioblastoma progression

Summary: Glioblastoma (GBM) is identified to share common signal pathways between glioma and immune cells. Here, we find that T cell immunoglobulin domain and mucin domain protein 3 (TIM-3) is one of the most common co-inhibitory immune checkpoints in GBM shared by tumor and non-tumor cells. Glioma...

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Hlavní autoři:	Qing Guo, Shuai Shen, Gefei Guan, Chen Zhu, Cunyi Zou, Jingyuan Cao, Wen Cheng, Xiaoyan Xu, Juanhan Yu, Zhiguo Lin, Guoli Wang, Ling Chen, Peng Cheng, Anhua Wu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2022-11-01
Edice:	iScience
Témata:	Cell biology Stem cells research Cancer
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2589004222016017
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