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Interactions between Calcium and Alpha-Synuclein in Neurodegeneration

In Parkinson’s disease and some atypical Parkinson’s syndromes, aggregation of the α-synuclein protein (α-syn) has been linked to neurodegeneration. Many triggers for pathological α-syn aggregation have been identified, including port-translational modifications, oxidative stress and raised metal i...

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Principais autores: Alex Rcom-H'cheo-Gauthier, Jacob Goodwin, Dean L. Pountney
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2014-08-01
coleção:Biomolecules
Assuntos:
alpha-synuclein
Parkinson’s disease
calcium
multiple system atrophy
neurodegeneration
oxidative stress
Acesso em linha:http://www.mdpi.com/2218-273X/4/3/795
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