Early Biomarkers of Altered Renal Function and Orthostatic Intolerance During 10-day Bedrest

Exposure to actual or simulated microgravity results in alterations of renal function, fluid redistribution, and bone loss, which is coupled to a rise of urinary calcium excretion. We provided evidence that high calcium delivery to the collecting duct reduces local Aquaporin 2 (AQP2)-mediated water...

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Autori principali:	Grazia Tamma, Annarita Di Mise, Marianna Ranieri, Mariangela Centrone, Maria Venneri, Mariagrazia D’Agostino, Angela Ferrulli, Boštjan Šimunič, Marco Narici, Rado Pisot, Giovanna Valenti
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2022-04-01
Serie:	Frontiers in Physiology
Soggetti:	bedrest vasopressin copeptin aquaporin-2 (AQP2) osteopontin adrenomedullin
Accesso online:	https://www.frontiersin.org/articles/10.3389/fphys.2022.858867/full
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