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Toll-like receptors 7 and 9 regulate the proliferation and differentiation of B cells in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune illness marked by the loss of immune tolerance and the production of autoantibodies against nucleic acids and other nuclear antigens (Ags). B lymphocytes are important in the immunopathogenesis of SLE. Multiple receptors control abnormal B-cell act...

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Hoofdauteurs: Luyao Wen, Bei Zhang, Xinfeng Wu, Rongzeng Liu, Hua Fan, Lei Han, Zhibo Zhang, Xin Ma, Cong-Qiu Chu, Xiaofei Shi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2023-02-01
Reeks:Frontiers in Immunology
Onderwerpen:
systemic lupus erythematosus
B cells
TLR signaling
TLR7
TLR9
targeted therapies
Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1093208/full
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