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A Novel Immunocompetent Mouse Model for Testing Antifungal Drugs Against Invasive <i>Candida albicans</i> Infection

Disseminated infection by <i>Candida</i> species represents a common, often life-threatening condition. Increased resistance to current antifungal drugs has led to an urgent need to develop new antifungal drugs to treat this pathogen. However, in vivo screening of candidate antifungal compounds requ...

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Principais autores: Lisa K. Ryan, Amy G Hise, Chowdhury Mobaswar Hossain, William Ruddick, Rezwana Parveen, Katie B. Freeman, Damian G. Weaver, Hema P. Narra, Richard W. Scott, Gill Diamond
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-09-01
coleção:Journal of Fungi
Assuntos:
mouse model
in vivo imaging
IVIS
host defense peptide
peptidomimetics
candidiasis
Acesso em linha:https://www.mdpi.com/2309-608X/6/4/197
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