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Screening Strategies for High-Yield Chinese Hamster Ovary Cell Clones

Chinese hamster ovary (CHO) cells are by far the most commonly used mammalian expression system for recombinant expression of therapeutic proteins in the pharmaceutical industry. The development of high-yield stable cell lines requires processes of transfection, selection, screening and adaptation,...

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Auteurs principaux: Wenwen Yang, Junhe Zhang, Yunxi Xiao, Wenqing Li, Tianyun Wang
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2022-06-01
Collection:Frontiers in Bioengineering and Biotechnology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fbioe.2022.858478/full
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