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Islet remodeling in female mice with spontaneous autoimmune and streptozotocin-induced diabetes.

Islet alpha- and delta-cells are spared autoimmune destruction directed at beta-cells in type 1 diabetes resulting in an apparent increase of non-beta endocrine cells in the islet core. We determined how islet remodeling in autoimmune diabetes compares to streptozotocin (STZ)-induced diabetes. Islet...

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Principais autores: Annette Plesner, Joris T Ten Holder, C Bruce Verchere
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC4125302?pdf=render
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