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How to improve the quality of euglycemic glucose clamp tests in long-acting insulin studies

Abstract Background The euglycemic clamp test stands as the best method for assessing the pharmacokinetic and pharmacodynamic properties of long-acting insulin. However, despite its widespread use, there remains a notable absence of an established gold standard for evaluating the test’s quality. Exi...

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Principais autores: Yi Yang, Fu Kuang, XueYing Zhu, Li Li, Yao Huang, Yang Liu, Xian Yu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-02-01
Serier:Trials
Fag:
Euglycemic glucose clamp test
Long-acting insulin
Quality control
Healthy volunteers
Blood glucose
C-peptide
Online adgang:https://doi.org/10.1186/s13063-025-08749-2
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