Optimization of THP-1-CAR monocytes utilizing CD32a signaling phagocytosis for antigen-specific T cell activation
Abstract Chimeric antigen receptor macrophages (CAR-M) are emerging as a next-generation cellular modality for therapies ranging from viral infection to solid tumors, leveraging innate phagocytic and antigen-presenting functions. Here, we compared CAR constructs incorporating intracellular signaling...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Portfolio
2026-02-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-026-39406-6 |
| Tags: |
No Tags, Be the first to tag this record!
|