Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and DifferentiationSummary

Background & Aims: Claudin-7 (Cldn7) is a tight junction (TJ) membrane protein located at the apical TJ and basolateral side of intestinal epithelial cells. Deletion of Cldn7 by gene targeting leads to the inflammatory bowel disease–like phenotype in mice, which includes weight loss, diarrhea, mucos...

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Detalhes bibliográficos

Principais autores:	Tiaosi Xing, Lesley Jasmine Benderman, Stephiya Sabu, Joel Parker, Jeffrey Yang, Qun Lu, Lei Ding, Yan-Hua Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2020-01-01
coleção:	Cellular and Molecular Gastroenterology and Hepatology
Assuntos:	Crypt Stem Cells Organoid Culture Wnt/β-Catenin Signaling
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352345X1930181X
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