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Endoplasmic reticulum stress aggravates ferroptosis via PERK/ATF4/HSPA5 pathway in UUO-induced renal fibrosis

Renal fibrosis, resulting from the transformation of damaged tubular epithelial cells (TECs), serves as a prevalent pathological condition observed in nearly all forms of advancing chronic kidney disease (CKD). Although crucial in fibrotic diseases, the association between endoplasmic reticulum stre...

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Váldodahkkit: Zhigang Huang, Lihua Zhou, Bin Liu, Xiaoju Li, Yu Sang
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2025-04-01
Ráidu:Frontiers in Pharmacology
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Liŋkkat:https://www.frontiersin.org/articles/10.3389/fphar.2025.1545972/full
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