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Identification of a new cell line permissive to porcine reproductive and respiratory syndrome virus infection and replication which is phenotypically distinct from MARC-145 cell line

<p>Abstract</p> <p>Background</p> <p>Airborne transmitted pathogens, such as porcine reproductive and respiratory syndrome virus (PRRSV), need to interact with host cells of the respiratory tract in order to be able to enter and disseminate in the host organism. Pulmonary alveolar macrophages (PAM)...

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Autori principali: Provost Chantale, Jia Jian Jun, Music Nedzad, Lévesque Cynthia, Lebel Marie-Ève, del Castillo Jérôme RE, Jacques Mario, Gagnon Carl A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2012-11-01
Serie:Virology Journal
Soggetti:
Porcine reproductive and respiratory syndrome virus
PRRSV
SJPL cells
Virus replication
Cell permissivity
Type 1 IFN
IFNγ
TNF-α
Cytokines
Accesso online:http://www.virologyj.com/content/9/1/267
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