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GV1001 reduces pathological 4R tau and functional deficits in models relevant to progressive supranuclear palsy

Abstract GV1001, a peptide drug derived from human telomerase reverse transcriptase, has showed the therapeutic effect in the animal model of Alzheimer’s disease (AD), a representative chronic neurodegenerative disease having impaired learning and memory. In our previous studies, GV1001 has showed t...

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Autori principali: Kyu-Beom Jang, Dong Min Kang, Myung-Hoon Lee, Nataliia Lukianenko, Yun Kyung Kim, Sungsu Lim, Sangjae Kim, Hyun Jin Cho
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2026-03-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-026-42195-7
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