Deep proteomic analysis of microglia reveals fundamental biological differences between model systems

Summary: Using high-resolution quantitative mass spectrometry, we present comprehensive human and mouse microglia proteomic datasets consisting of over 11,000 proteins across six microglia groups. Microglia share a core protein signature of over 5,600 proteins, yet fundamental differences are observ...

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Detalhes bibliográficos

Principais autores:	Amy F. Lloyd, Anna Martinez-Muriana, Emma Davis, Michael J.D. Daniels, Pengfei Hou, Renzo Mancuso, Alejandro J. Brenes, Linda V. Sinclair, Ivana Geric, An Snellinx, Katleen Craessaerts, Tom Theys, Mark Fiers, Bart De Strooper, Andrew J.M. Howden
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-11-01
coleção:	Cell Reports
Assuntos:	CP: Neuroscience
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124724012592
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