Molecular Dynamic Simulation Analysis of a Novel Missense Variant in <i>CYB5R3</i> Gene in Patients with Methemoglobinemia

<i>Background and Objective</i>: Mutations in the <i>CYB5R3</i> gene cause reduced NADH-dependent cytochrome b5 reductase enzyme function and consequently lead to recessive congenital methemoglobinemia (RCM). RCM exists as RCM type I (RCM1) and RCM type II (RCM2). RCM1 leads to higher methemoglobin...

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Autori principali:	Asmat Ullah, Abid Ali Shah, Fibhaa Syed, Arif Mahmood, Hassan Ur Rehman, Beenish Khurshid, Abdus Samad, Wasim Ahmad, Sulman Basit
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2023-02-01
Serie:	Medicina
Soggetti:	recessive congenital methemoglobinemia (RCM) exome sequencing <i>CYB5R3</i> molecular dynamics simulation
Accesso online:	https://www.mdpi.com/1648-9144/59/2/379
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