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Structure of the human transcobalamin beta domain in four distinct states.

Vitamin B12 (cyanocobalamin, CNCbl) is an essential cofactor-precursor for two biochemical reactions in humans. When ingested, cobalamins (Cbl) are transported via a multistep transport system into the bloodstream, where the soluble protein transcobalamin (TC) binds Cbl and the complex is taken up i...

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Autori principali: Joël S Bloch, Markus Ruetz, Bernhard Kräutler, Kaspar P Locher
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2017-01-01
Serie:PLoS ONE
Accesso online:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184932&type=printable
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