Genome-Wide Transcriptional Response of Mycobacterium smegmatis MC2155 to G-Quadruplex Ligands BRACO-19 and TMPyP4

G-quadruplexes (G4s) are non-canonical DNA structures that could be considered as potential therapeutic targets for antimicrobial compounds, also known as G4-stabilizing ligands. While some of these ligands are shown in vitro to have a stabilizing effect, the precise mechanism of antibacterial actio...

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Detalhes bibliográficos

Principais autores:	Egor Shitikov, Dmitry Bespiatykh, Maja Malakhova, Julia Bespyatykh, Ivan Bodoev, Tatiana Vedekhina, Marina Zaychikova, Vladimir Veselovsky, Ksenia Klimina, Elena Ilina, Anna Varizhuk
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-03-01
coleção:	Frontiers in Microbiology
Assuntos:	mycobacteria transcriptome RNA G4 ligands BRACO-19
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmicb.2022.817024/full
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