Specificity for deubiquitination of monoubiquitinated FANCD2 is driven by the N-terminus of USP1
Deubiquitination of FANCD2, FANCI, and PCNA by USP1 is essential for DNA repair signalling. Reconstitution of the system reveals that USP1-mediated specificity towards K561 of FANCD2 is directed by a unique sequence at USP1's N-terminus. The Fanconi anemia pathway for DNA interstrand crosslink repai...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Life Science Alliance LLC
2018-10-01
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| Serie: | Life Science Alliance |
| Accesso online: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.201800162 |
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