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Thriving under stress: selective translation of HIV-1 structural protein mRNA during Vpr-mediated impairment of eIF4E translation activity.

Translation is a regulated process and is pivotal to proper cell growth and homeostasis. All retroviruses rely on the host translational machinery for viral protein synthesis and thus may be susceptible to its perturbation in response to stress, co-infection, and/or cell cycle arrest. HIV-1 infectio...

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Autores principales: Amit Sharma, Alper Yilmaz, Kim Marsh, Alan Cochrane, Kathleen Boris-Lawrie
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2012-01-01
Colección:PLoS Pathogens
Acceso en línea:http://europepmc.org/articles/PMC3310836?pdf=render
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