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Prevention of Autoimmune Diabetes in NOD Mice by Dimethyl Fumarate

Oxidative stress plays critical roles in the pathogenesis of diabetes. This study tested the hypothesis that by protecting β-cells against oxidative stress and inflammation, an Nrf2 activator, dimethyl fumarate (DMF), may prevent or delay the onset of type 1 diabetes in non-obese diabetic (NOD) mice...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Shiri Li, Nosratola D. Vaziri, Lourdes Swentek, Chie Takasu, Kelly Vo, Michael J. Stamos, Camillo Ricordi, Hirohito Ichii
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-01-01
Schriftenreihe:Antioxidants
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Online-Zugang:https://www.mdpi.com/2076-3921/10/2/193
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