QbD-based optimization of wet milling for the synthesis of glimepiride-metformin HCl nano-cocrystal suspension using various stabilizers
Glimepiride (GLI) and metformin HCl (MET) are widely co-administered as oral antidiabetic agents for type 2 diabetes mellitus (T2DM). From a crystal engineering perspective, this combination can be developed into a multidrug cocrystal (CC) to improve physicochemical properties. With appropriate stab...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Pensoft Publishers
2025-10-01
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| Schriftenreihe: | Pharmacia |
| Online-Zugang: | https://pharmacia.pensoft.net/article/158758/download/pdf/ |
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