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NF-κB在卵巢癌顺铂耐药株COC1/DDP中的表达及意义

目的探讨NF-κB在卵巢癌COC1/DDP顺铂耐药中的生物学作用。方法应用Westernblot法检测COC1、COC1/DDP两细胞株细胞核内NF-κB p65蛋白表达差异。结果COC1/DDP细胞核内NF-κB p65蛋白表达明显高于亲本株COC1。结论COC1/DDP对顺铂耐药可能与NF-κB核内活化表达有关。

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Bibliographic Details
Main Authors: 何凯, 雷娟, 卢战凯, 许天敏, 李源, 李云波, 张雪芹, 杜绍敏
Format: Artigo
Language:Chinês
Published: Editorial Office of Chinese Journal of Laboratory Diagnosis 2008-01-01
Series:Zhongguo shiyan zhenduanxue
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Online Access:http://ZSZD.publish.founderss.cn/thesisDetails?columnId=88536543&Fpath=home&index=0
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