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Therapeutic potential of alternative splicing in cardiovascular diseases

Summary: RNA splicing is an important RNA processing step required by multiexon protein-coding mRNAs and some noncoding RNAs. Precise RNA splicing is required for maintaining gene and cell function; however, mis-spliced RNA transcripts can lead to loss- or gain-of-function effects in human diseases....

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Bibliografische Detailangaben
Hauptverfasser: Jun Cao, Ziyu Wei, Yu Nie, Hou-Zao Chen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2024-03-01
Schriftenreihe:EBioMedicine
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2352396424000306
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