Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in <it>Drosophila </it>and is essential for starvation resistance
<p>Abstract</p> <p>Background</p> <p>Insulin and insulin-like growth factors (IGFs) signal through a highly conserved pathway and control growth and metabolism in both vertebrates and invertebrates. In mammals, insulin-like growth factor binding proteins (IGFBPs) bind IGFs with high affinity and mod...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2008-04-01
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| coleção: | Journal of Biology |
| Acesso em linha: | http://jbiol.com/content/7/3/10 |
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