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Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination

Abstract Background This clinical trial evaluated a novel telomerase-targeting therapeutic cancer vaccine, UV1, in combination with ipilimumab, in patients with metastatic melanoma. Translational research was conducted on patient-derived blood and tissue samples with the goal of elucidating the effe...

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Збережено в:
Бібліографічні деталі
Автори: Espen Basmo Ellingsen, Gergana Bounova, Iliana Kerzeli, Irantzu Anzar, Donjete Simnica, Elin Aamdal, Tormod Guren, Trevor Clancy, Artur Mezheyeuski, Else Marit Inderberg, Sara M. Mangsbo, Mascha Binder, Eivind Hovig, Gustav Gaudernack
Формат: Artigo
Мова:Inglês
Опубліковано: BMC 2022-09-01
Серія:Journal of Translational Medicine
Предмети:
Онлайн доступ:https://doi.org/10.1186/s12967-022-03624-z
Теги: Додати тег
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