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Roles of TLR7 in Schistosoma japonicum Infection-Induced Hepatic Pathological Changes in C57BL/6 Mice

S. japonicum infection can induce granulomatous inflammation in the liver of the host. Granulomatous inflammation limits the spread of infection and plays a role in host protection. Toll-like receptor 7 (TLR7) is an endosomal TLR that recognizes single-stranded RNA (ssRNA). In this study, the role o...

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Main Authors: Yuanfa Feng, Hongyan Xie, Feihu Shi, Dianhui Chen, Anqi Xie, Jiajie Li, Chao Fang, Haixia Wei, He Huang, Xingfei Pan, Xiaoping Tang, Jun Huang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
TLR7
S. japonicum
hepatic inflammation
Th2
macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.754299/full
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