Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation

Cancer-associated fibroblasts (CAFs) are involved in the proliferative and invasive behavior of colorectal cancer (CRC). Nonetheless, CAFs represent a heterogeneous population with both cancer-promoting and cancer-restraining actions, lacking specific markers to target them. Expression of the immune...

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Detalhes bibliográficos

Principais autores:	Julie Jacobs, Vanessa Deschoolmeester, Karen Zwaenepoel, Tal Flieswasser, Christophe Deben, Jolien Van den Bossche, Christophe Hermans, Christian Rolfo, Marc Peeters, Olivier De Wever, Filip Lardon, Vasiliki Siozopoulou, Evelien Smits, Patrick Pauwels
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2018-07-01
coleção:	OncoImmunology
Assuntos:	cancer-associated fibroblasts cd70 regulatory t cells colorectal cancer biomarker migration prognosis immunotherapy tumor microenvironment
Acesso em linha:	http://dx.doi.org/10.1080/2162402X.2018.1440167
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