Multiregional single-cell transcriptomics reveals an association between partial EMT and immunosuppressive states in oral squamous cell carcinoma

Summary: Oral squamous cell carcinoma (OSCC) is highly heterogeneous and metastatic, and the mechanisms driving OSCC development, progression, and metastasis remain elusive. Here, we performed single-cell RNA sequencing on 231,442 cells obtained from the tumor core (TC), tumor periphery (TP), adjace...

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Detaylı Bibliyografya
Asıl Yazarlar:	Seunghoon Kim, Hyun Jung Kee, Dahee Kim, Jinho Jang, Hyoung-oh Jeong, Nam Suk Sim, Mischa Selig, Jana Ihlow, Livius Penter, Taejoo Hwang, David Whee-Young Choi, Kyoung Jun Lee, Jaewoong Lee, Young Min Park, Semin Lee, Yoon Woo Koh
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Elsevier 2025-09-01
Seri Bilgileri:	iScience
Konular:	Microenvironment
Online Erişim:	http://www.sciencedirect.com/science/article/pii/S2589004225012490
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Multiregional single-cell transcriptomics reveals an association between partial EMT and immunosuppressive states in oral squamous cell carcinoma

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