Targeting MAN1B1 potently enhances bladder cancer antitumor immunity via deglycosylation of CD47

Abstract Background Only a few bladder cancer patients benefit from anti‐programmed cell death protein 1/programmed cell death ligand 1 immunotherapy. The cluster of differentiation 47 (CD47) plays an important role in tumor immune evasion. CD47 is a highly glycosylated protein, however, the mechani...

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Principais autores:	Jie Zhang, Chen Zhang, Ruichen Zang, Weiwu Chen, Yining Guo, Haofei Jiang, Jing Le, Kunyu Wang, Haobo Fan, Xudong Wang, Sisi Mo, Peng Gao, Wenhao Guo, Xinrong Jiang, Fengbin Gao, Junming Jiang, Juyan Zheng, Yuxing Chen, Yicheng Chen, Yanlan Yu, Guoqing Ding
格式:	Artigo
語言:	Inglês
出版:	Wiley 2025-09-01
叢編:	Cancer Communications
主題:	Bladder cancer cluster of differentiation 47 mannosidase alpha class 1B member 1 immunotherapy macrophage phagocytosis
在線閱讀:	https://doi.org/10.1002/cac2.70040
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