MTNR1B variants increase gestational diabetes mellitus risk in young Chinese pregnant women

Abstract The aim of this study is to explore the relationship between the MTNR1B gene variants rs1387153 and rs10830963 and the risk of gestational diabetes mellitus (GDM). Additionally, the study sought to investigate gene-environment interactions, assess the cumulative genetic risk through the app...

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Hlavní autoři:	Qiaoli Zeng, Xin Liu, Jia Liu, Yanying Wu, Yuxuan Zhang, Zhaotao He, Yue Wei, Guofang Zeng, Dehua Zou, Runmin Guo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-06-01
Edice:	Scientific Reports
Témata:	Gestational diabetes mellitus MTNR1B polymorphisms Gene-environment interactions Genetic risk scores Predictive model
On-line přístup:	https://doi.org/10.1038/s41598-025-02248-9
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