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Protective Effects of Rapamycin on Trabecular Meshwork Cells in Glucocorticoid-Induced Glaucoma Mice

Glucocorticoid-induced glaucoma (GIG) is a chronic optic neuropathy caused by systemic or topical glucocorticoid (GC) treatment, which could eventually lead to permanent vision loss. To investigate the protective effects of rapamycin (RAP) on the trabecular cells during the development of GIG in mic...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Xiaolu Zhu, Shengyu Wu, Wen Zeng, Xiaomin Chen, Tian Zheng, Jiangbo Ren, Min Ke
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020-07-01
Schriftenreihe:Frontiers in Pharmacology
Schlagworte:
glucocorticoid-induced glaucoma
trabecular meshwork
dexamethasone
autophagy
rapamycin
Online-Zugang:https://www.frontiersin.org/article/10.3389/fphar.2020.01006/full
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