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Synthesis and Chemopreventive Potential of 5-FU/Genistein Hybrids on Colorectal Cancer Cells

A series of 5-FU-Genistein hybrids were synthesized and their structures were elucidated by spectroscopic analysis. The chemopreventive potential of these compounds was evaluated in human colon adenocarcinoma cells (SW480 and SW620) and non-malignant cell lines (HaCaT and CHO-K1). Hybrid <b>4a</b> d...

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Principais autores: Gustavo Moreno-Quintero, Wilson Castrillón-Lopez, Angie Herrera-Ramirez, Andrés F. Yepes-Pérez, Jorge Quintero-Saumeth, Wilson Cardona-Galeano
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-10-01
coleção:Pharmaceuticals
Assuntos:
5-FU
genistein
hybrid compounds
colorectal cancer
cytotoxicity
antiproliferative activity
Acesso em linha:https://www.mdpi.com/1424-8247/15/10/1299
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