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Feature learning augmented with sampling and heuristics (FLASH) improves model performance and biomarker identification

Abstract Big biological datasets, such as gene expression profiles, often contain redundant features that degrade model performance and limit generalization across independent datasets with complexities like class imbalance and hidden sub-clusters. To overcome challenges, we present ‘FLASH’, a novel...

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Hlavní autoři: Shivam Kumar, Abhinav Agarwal, Samrat Chatterjee
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2025-12-01
Edice:npj Systems Biology and Applications
On-line přístup:https://doi.org/10.1038/s41540-025-00614-x
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