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Genome-wide DNA methylation and RNA-seq analyses identify genes and pathways associated with doxorubicin resistance in a canine diffuse large B-cell lymphoma cell line.

Doxorubicin resistance is a major challenge in the successful treatment of canine diffuse large B-cell lymphoma (cDLBCL). In the present study, MethylCap-seq and RNA-seq were performed to characterize the genome-wide DNA methylation and differential gene expression patterns respectively in CLBL-1 8....

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Autori principali: Chia-Hsin Hsu, Hirotaka Tomiyasu, Chi-Hsun Liao, Chen-Si Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2021-01-01
Serie:PLoS ONE
Accesso online:https://doi.org/10.1371/journal.pone.0250013
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