Proton Craniospinal Irradiation with Immunotherapy in Two Patients with Leptomeningeal Disease from Melanoma

Introduction Proton craniospinal irradiation (pCSI) is a treatment option for leptomeningeal disease (LMD), which permits whole neuroaxis treatment while minimizing toxicity. Despite this, patients inevitably experience progression. Adding systemic therapy to pCSI may improve outcomes. Methods In th...

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Hauptverfasser:	Ugur Sener, Mason Webb, William G. Breen, Bryan J. Neth, Nadia N. Laack, David Routman, Paul D. Brown, Anita Mahajan, Kelsey Frechette, Arkadiusz Z. Dudek, Svetomir N. Markovic, Matthew S. Block, Robert R. McWilliams, Anastasios Dimou, Lisa A. Kottschade, Heather N. Montane, Sani H. Kizilbash, Jian L. Campian
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Innovative Healthcare Institute 2024-02-01
Schriftenreihe:	Journal of Immunotherapy and Precision Oncology
Schlagworte:	leptomeningeal disease proton therapy craniospinal irradiation immune checkpoint inhibitors immunotherapy
Online-Zugang:	https://jipo.org/doi/pdf/10.36401/JIPO-23-20
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