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Increased expression of miR‐641 contributes to erlotinib resistance in non‐small‐cell lung cancer cells by targeting NF1

Abstract Epidermal growth receptor (EGFR)‐targeted tyrosine kinase inhibitors (TKIs) have emerged as first‐line drugs for advanced non‐small‐cell lung cancer (NSCLC) patients with EFGR mutations. However, most patients with NSCLC show acquired resistance to EGFR‐TKIs, and low expression of NF1 is a...

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Detalles Bibliográficos
Principais autores: Juan Chen, Jie‐da Cui, Xiao‐tong Guo, Xia Cao, Qing Li
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2018-04-01
Series:Cancer Medicine
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Acceso en liña:https://doi.org/10.1002/cam4.1326
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