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Large-scale lipidomic profiling identifies novel potential biomarkers for prion diseases and highlights lipid raft-related pathways

Abstract Prion diseases are transmissible spongiform encephalopathies induced by the abnormally-folded prion protein (PrPSc), which is derived from the normal prion protein (PrPC). Previous studies have reported that lipid rafts play a pivotal role in the conversion of PrPC into PrPSc, and several t...

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Hlavní autoři: Yong-Chan Kim, Junbeom Lee, Dae-Weon Lee, Byung-Hoon Jeong
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2021-07-01
Edice:Veterinary Research
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On-line přístup:https://doi.org/10.1186/s13567-021-00975-1
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