Paclitaxel-coated balloon treatment is associated with sympathetic coronary denervation in a porcine model

Abstract Drug-coated balloon (DCB) therapy promotes beneficial vascular remodeling after percutaneous coronary intervention. However, its mechanisms remain elusive. Given paclitaxel’s neurotoxicity, the effects of paclitaxel (PTX)-DCB treatment on periarterial innervation are unknown. This study ass...

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Detalhes bibliográficos

Principais autores:	Mert Tokcan, Stephanie Bettink, Ole Gemeinhardt, Saarraaken Kulenthiran, Michael Böhm, Felix Mahfoud, Bruno Scheller
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-06-01
coleção:	Scientific Reports
Assuntos:	DCB Drug-coated balloon Coronary innervation Late lumen enlargement Periarterial sympathetic nerves
Acesso em linha:	https://doi.org/10.1038/s41598-026-54572-3
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