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On the effects of alternative optima in context-specific metabolic model predictions.

The integration of experimental data into genome-scale metabolic models can greatly improve flux predictions. This is achieved by restricting predictions to a more realistic context-specific domain, like a particular cell or tissue type. Several computational approaches to integrate data have been p...

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Bibliografische Detailangaben
Hauptverfasser: Semidán Robaina-Estévez, Zoran Nikoloski
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2017-05-01
Schriftenreihe:PLoS Computational Biology
Online-Zugang:https://doi.org/10.1371/journal.pcbi.1005568
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