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In Search of Differential Inhibitors of Aldose Reductase

Aldose reductase, classified within the aldo-keto reductase family as AKR1B1, is an NADPH dependent enzyme that catalyzes the reduction of hydrophilic as well as hydrophobic aldehydes. AKR1B1 is the first enzyme of the so-called polyol pathway that allows the conversion of glucose into sorbitol, whi...

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Hlavní autoři: Francesco Balestri, Roberta Moschini, Umberto Mura, Mario Cappiello, Antonella Del Corso
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2022-03-01
Edice:Biomolecules
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On-line přístup:https://www.mdpi.com/2218-273X/12/4/485
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