The crystal structure of Toxoplasma gondii pyruvate kinase 1.
Pyruvate kinase (PK), which catalyzes the final step in glycolysis converting phosphoenolpyruvate to pyruvate, is a central metabolic regulator in most organisms. Consequently PK represents an attractive therapeutic target in cancer and human pathogens, like Apicomplexans. The phylum Aplicomplexa, a...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2010-09-01
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| Series: | PLoS ONE |
| Acceso en liña: | http://europepmc.org/articles/PMC2939071?pdf=render |
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