Keratinocyte HIF-1α Orchestrates Imiquimod-Induced Psoriasiform Inflammation by Promoting Type 3 Inflammation
Psoriasis is a chronic inflammatory skin disease driven by the IL-23/IL-17 axis and characterized by keratinocyte hyperproliferation, epidermal thickening, and immune infiltration. While immune cell-intrinsic roles of hypoxia-inducible factor-1α (HIF-1α) have been reported, the contribution of kerat...
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| Format: | Artigo |
| Sprache: | Inglês |
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MDPI AG
2025-12-01
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| Schriftenreihe: | Biomedicines |
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| Online-Zugang: | https://www.mdpi.com/2227-9059/14/1/65 |
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