Modulation of Human Dendritic Cell Functions by Phosphodiesterase-4 Inhibitors: Potential Relevance for the Treatment of Respiratory Diseases

Inhibitors of phosphodiesterase-4 (PDE4) are small-molecule drugs that, by increasing the intracellular levels of cAMP in immune cells, elicit a broad spectrum of anti-inflammatory effects. As such, PDE4 inhibitors are actively studied as therapeutic options in a variety of human diseases characteri...

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Auteurs principaux:	Hoang Oanh Nguyen, Laura Tiberio, Fabrizio Facchinetti, Giulia Ripari, Valentina Violi, Gino Villetti, Valentina Salvi, Daniela Bosisio
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2023-08-01
Collection:	Pharmaceutics
Sujets:	cDC1 cDC2 pDC monocyte-derived DC tolerogenic DCs CD80
Accès en ligne:	https://www.mdpi.com/1999-4923/15/9/2254
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