Antibody-induced erythrophagocyte reprogramming of Kupffer cells prevents anti-CD40 cancer immunotherapy-associated liver toxicity
Background Agonistic anti-CD40 monoclonal antibodies (mAbs) have emerged as promising immunotherapeutic compounds with impressive antitumor effects in mouse models. However, preclinical and clinical studies faced dose-limiting toxicities mediated by necroinflammatory liver disease. An effective prop...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , , , , , , , |
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| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
BMJ Publishing Group
2023-01-01
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| মালা: | Journal for ImmunoTherapy of Cancer |
| অনলাইন ব্যবহার করুন: | https://jitc.bmj.com/content/11/1/e005718.full |
| ট্যাগগুলো: |
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