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Low dosage of histone H4 leads to growth defects and morphological changes in Candida albicans.

Chromatin function depends on adequate histone stoichiometry. Alterations in histone dosage affect transcription and chromosome segregation, leading to growth defects and aneuploidies. In the fungal pathogen Candida albicans, aneuploidy formation is associated with antifungal resistance and pathogen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lucia F Zacchi, Anna M Selmecki, Judith Berman, Dana A Davis
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2010-05-01
Saila:PLoS ONE
Sarrera elektronikoa:http://europepmc.org/articles/PMC2869362?pdf=render
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