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Astragaloside IV Alleviates DSS-Induced Ulcerative Colitis by Modulating Host–Gut Tryptophan Metabolism

Astragaloside IV (AS-IV), a principal bioactive constituent of the medicinal and edible herb <i>Radix astragali</i>, exerts protective effects against ulcerative colitis (UC). This study investigated its underlying mechanisms in dextran sulfate sodium (DSS)-induced colitis using 16S rRNA sequencing,...

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Principais autores: Hongxia Yuan, Zhijun Yang, Chunmei Wu, Xinyu Chen, Lili Peng, Yajie Liu, Xinyi Wang, Yuanbiao Qiao, Fan Yang, Rui Ge, Qingshan Li
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-05-01
Serier:Foods
Fag:
Astragaloside IV
ulcerative colitis
gut microbiota
tryptophan metabolism
AhR
NF-κB p65
Online adgang:https://www.mdpi.com/2304-8158/15/10/1644
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