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BayesPI-BAR2: A New Python Package for Predicting Functional Non-coding Mutations in Cancer Patient Cohorts

Most of somatic mutations in cancer occur outside of gene coding regions. These mutations may disrupt the gene regulation by affecting protein-DNA interaction. A study of these disruptions is important in understanding tumorigenesis. However, current computational tools process DNA sequence variants...

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Bibliografiske detaljer
Principais autores: Kirill Batmanov, Jan Delabie, Junbai Wang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019-04-01
Serier:Frontiers in Genetics
Fag:
Online adgang:https://www.frontiersin.org/article/10.3389/fgene.2019.00282/full
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