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CS2164 combined with radiation suppressed tumor growth via γ-H2AX persistence and ROS accumulation

Abstract Background CS2164 is an oral multi-target inhibitor that targets angiogenesis-related kinases, mitosis-related kinases, and chronic inflammation-related kinases. However, the added clinical benefit of CS2164 combined with radiation remains unknown. Methods The anti-tumor effect of CS2164 co...

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Principais autores: Shun-li Peng, Yu-ling Zhou, Xuexia Liang, Ren-wei Jiang, Shuai Yang, Qiao-dan Liu, Xiao-mou Peng
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2026-03-01
סדרה:BMC Cancer
נושאים:
CS2164
Radiation
DNA damage response
Redox imbalance
גישה מקוונת:https://doi.org/10.1186/s12885-026-15865-y
תגים: הוספת תג
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