H3K27me3 and HOXA9 expression predict prognosis in pediatric acute myeloid leukemia: an epigenetic-transcriptional correlation study

BackgroundEpigenetic dysregulation plays a central role in pediatric acute myeloid leukemia (AML), yet its clinical relevance remains underexplored. This study primarily aimed to elucidate the clinical effect of H3K27me3 and H3K4me3 status on pediatric acute myeloid leukemia. We evaluated the progno...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Hironori Goto, Souichi Suenobu, Yuhki Koga, Shunsuke Yamamoto, Kentaro Nakashima, Utako Oba, Daiichiro Hasegawa, Ikuya Usami, Ayako Yamamori, Hiroshi Moritake, Sumihito Nobusawa, Keisuke Okuno, Koji Kawaguchi, Miyako Kanno, Hisashi Ishida, Yuko Cho, Haruto Nishida, Daisuke Tomizawa, Kenji Ihara, Shouichi Ohga
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Frontiers Media S.A. 2025-09-01
Reeks:	Frontiers in Hematology
Onderwerpen:	H3K27me3 pediatric AML HOXA9 H3K4Me3 HOXA cluster genes
Online toegang:	https://www.frontiersin.org/articles/10.3389/frhem.2025.1668408/full
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!